Uncomplicated Upper tract
Uncomplicated Upper Tract
Pyelonephritis
Bottom Line
- Treatment of pyelonephritis is 7 days if a fluoroquinolone (FQ) is used and 14 days with any other antibiotic.
- Treatment can be changed from IV to PO when afebrile x 48h
- Enterococci are implicated in < 20% of acute UTI.
- Most antibiotics achieve sufficiently high enough concentrations in urine to overcome reported resistance.
Inpatient
- Ceftriaxone 1g IV Daily x 14d OR
- Ciprofloxacin 400MG IV BID (or 500MG PO BID) x 7 days OR
- Levofloxacin 750MG Daily x 7 days
Outpatient
- Ciprofloxacin 500MG PO BID x 7 days OR
- Levofloxacin 750MG PO Daily x 5 days OR
- TMP/SMX DS PO Daily x 14d