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Clinical Condition
Meningitis
Respiratory
Endocarditis
Intra-abdominal
Urinary Tract Infection
Skin and Soft tissue
Skeletal (Bone & Joints)
Bacteremia and Undifferentiated
Microbiology
Gram positive cocci
Gram negative bacilli
Antibiotics
Penicillin
Ampicillin
Oxacillin
Cefazolin
Cefuroxime
Ceftriaxone
Ceftazidime
Imipenem
Meropenem
Piperacillin-Tazobactam
Ticarcillin-Clavulanic acid
Trimethroprim/Sulfamethoxazole
Ciprofloxacin
Levofloxacin
Gentamicin
High Level Gentamicin
High Level Streptomycin
Tobramycin
Tetracycline
Erythromycin
Clindamycin
Nitrofurantoin
Location
Meningitis
Meningitis
Bottom Line
The use of empiric vancomycin is
NOT
necessary as the incidence of high-level penicillin resistant
S. pneumoniae
is very low.
If concern for
Listeria monocytogenes
(elderly, alcoholic), then ampicillin can be added
Do not forget to add
dexamethasone
to your regimen.
Empiric Therapy
Ceftriaxone
2 g IV q12h
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