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Clinical Condition
Meningitis
Respiratory
Endocarditis
Intra-abdominal
Urinary Tract Infection
Skin and Soft tissue
Skeletal (Bone & Joints)
Bacteremia and Undifferentiated
Microbiology
Gram positive cocci
Gram negative bacilli
Antibiotics
Penicillin
Ampicillin
Oxacillin
Cefazolin
Cefuroxime
Ceftriaxone
Ceftazidime
Imipenem
Meropenem
Piperacillin-Tazobactam
Ticarcillin-Clavulanic acid
Trimethroprim/Sulfamethoxazole
Ciprofloxacin
Levofloxacin
Gentamicin
High Level Gentamicin
High Level Streptomycin
Tobramycin
Tetracycline
Erythromycin
Clindamycin
Nitrofurantoin
Location
Uncomplicated Lower tract
Uncomplicated Lower Tract
Uncomplicated lower tract is classified as patients that are immunocompetent, without structural disease and not pregnant.
Cystitis
Bottom Line
DO NOT TREAT
patients with
AS
Y
MPTOMATIC
bacteriuria
unless they are pregnant.
Amoxicillin or ampicillin should
NOT
be used as empiric treatment due to poor efficacy and high rates of antimicrobial resistance amongst common Gram negative bacilli (GNBs).
Fluoroquinolones (FQs) should be used for 3 days only.
Risk of pulmonary fibrosis with prolonged or recurrent nitrofurantoin use.
Empiric Therapy
Nitrofurantoin
100MG PO BID x 5d
TMP/SMX
160/800MG (1 DS tab) PO BID
x 3d
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